Spider Man 2 is based on the classic Marvel Comics hero, Tobey Maguire returns as the mild-mannered Peter Parker, who is juggling the delicate balance of his dual life as college student and a superhuman crime fighter. Peter's life becomes even more complicated when he confronts a new nemesis, the brilliant Otto Octavius (Alfred Molina) who has been reincarnated as the maniacal and multi-tentacled "Doc Ock." When Doc Ock kidnaps MJ (Kirsten Dunst), Spider-Man must swing back into action as the adventure reaches new heights of unprecedented excitement.
Peter Parker is finding his double life increasingly difficult. Precariously struggling to balance his crime-fighting duties with the demands of his normal life, Peter often finds his personal life taking a back seat. He loses a job, faces financial difficulties, and struggles to maintain his physics studies at Columbia University. Moreover, he has become estranged from both love interest Mary Jane, who to Peter's disappointment is in a relationship, and best friend Harry Osborn who falsely accuses Spider-Man of murdering his father, and Aunt May is threatened with foreclosure.